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Nolvadex (Tamoxifen)

Nolvadex (Tamoxifen)

Nolvadex is a modern drug mainly used to prevent the risk of breast cancer and to treat the disease. Nolvadex is an anti-estrogenic agent, inhibiting estrogen and suppressing tumor growth.

You can also use the medication to treat other conditions. Moreover, Nolvadex PCT (Post Cycle Therapy), which makes it possible to neutralize the effects of steroids, is widely used in bodybuilding.

Active Ingredient: Tamoxifen Citrate

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Nolvadex Generic


Drug Info

  • Brand Names: Nolvadex, Tamoxican, Tamilong;
  • Active Ingredient: Tamoxifen Citrate;
  • Manufacturer: AstraZeneca.

Nolvadex and its active substance Tamoxifen

The active ingredient of Nolvadex is Tamoxifen. It is an estrogen antagonist, also having a selective stimulating effect on estrogen receptors. In the cells of the mammary gland, it plays the role of an anti-estrogen, and in the cells of other tissues (bones, uterus), Tamoxifen acts as an estrogen.

The effect of the drug depends on the purpose of its use. Tamoxifen suppresses tumor growth when used to treat breast cancer. After you take the pill, the drug substance gets into the blood and blocks estrogen receptors in the mammary gland, preventing estrogen from reaching cancer cells.

Indications for use

Nolvadex is mainly used for the treatment of estrogen-dependent diseases. The main indications for using the drug are as follows:

  • Breast cancer;
  • Primary prevention of breast cancer in women at high and moderate risk;
  • Anovulatory infertility.

Using Nolvadex in bodybuilding is common to reduce estrogen and prevent gynecomastia in men.

Treatment regimens and dosages

The drug is available in dosages of 10 mg and 20 mg. Depending on the disease and individual characteristics, the doctor prescribes a dosage and treatment regimen. The following dosages and treatment regimens are usually used:

  • For breast cancer, the standard recommended daily dosage is Nolvadex 20 mg. The doctor determines the treatment duration based on the disease's severity and other factors.
  • Nolvadex 20 mg is also used for the primary prevention of breast cancer, with a treatment duration of about 5 years.
  • For anovulatory infertility, the starting dose is Nolvadex 20 mg on the cycle's second, third, fourth, and fifth days. Then, you can increase the daily dosage to 40 mg if required.

You can take the drug once or twice a day. The doctor may decrease or increase the daily dosage if appropriate. Follow the doctor's recommendations, and don't change the dosage on your own.

Older people can use the same dosages, as there is no evidence that their response to Tamoxifen differs from that of younger people.

Nolvadex may affect thyroid function test results. So, inform them about taking the drug before the test.

Recommendations for use

Nolvadex is available as an oral tablets. To get the maximum effect from the medication, follow these rules:

  • Take the drug at the same time;
  • Don't crush the pill before use;
  • Take the tablet with plenty of water;
  • If you take several tablets at a time, take each of them with water.
  • Take the drug before or after meals.

During treatment, you should minimize or stop drinking alcohol, as it may increase the side effects of Tamoxifen and reduce the effectiveness of treatment. If you can't completely give up alcohol, ask the doctor to determine your acceptable limit.

Grapefruits (and grapefruit juice) and tangerines can also lower the effectiveness of the medicine.

Missed Dose

Follow the treatment regimen, and don't miss doses. If you miss a dose, your next action depends on how many times a day you take the drug:

  • If you take the medication once a day and if less than 12 hours have passed since the last dose, take the prescribed single dose of Nolvadex. If more than 12 hours have passed, skip the dose and wait until your next dose.
  • If you take the drug twice a day, take the missed dose as soon as you remember. If it is near time for your next dose, take only that dose. Then, return to your regular Nolvadex treatment regimen. Don't take a double or extra dose.


Before treatment, inform the doctor about all your diseases. In some cases, a doctor should control the treatment. These cases include:

  • Drug allergies;
  • Deep vein thrombosis;
  • Pulmonary embolism;
  • Heart stroke;
  • High cholesterol;
  • Diabetes;
  • Hypertension;
  • Cataract;
  • Liver disease.

Individual intolerance, pregnancy, and breastfeeding are among the medicine contraindications.

Use of Nolvadex during pregnancy

Pregnant women shouldn't use the drug due to the high risk to the fetus. Moreover, during treatment, you should avoid pregnancy using proven contraception methods. If you get pregnant while using Nolvadex, stop taking the drug immediately and inform the doctor.

Currently, there is no data on whether Tamoxifen gets into breast milk. So, due to the possible risk to the child, you shouldn't also use the drug during breastfeeding.

Nolvadex in bodybuilding

In bodybuilding, Nolvadex PCT (Post Cycle Therapy) is an effective way to avoid the effects of steroids. The drug also helps reduce estrogen levels and improve training results.

You can also use Nolvadex for gyno (gynecomastia) in men. Anabolic steroids may cause gynecomastia. So, after taking these drugs, you can use Nolvadex to prevent this medical condition. Using Nolvadex in bodybuilding has these benefits:

  • Restoring hormonal levels;
  • Preventing gynecomastia;
  • Preventing other side effects of steroid drugs;
  • Improving skin and hair condition;
  • Decreasing blood pressure;
  • Reducing cholesterol.

Possible Nolvadex side effects

Usually, people tolerate the drug well, and possible side effects are mild and go away with time. The most common side effects are as follows:

  • Headache;
  • Nausea;
  • Leg cramps;
  • Flushes of blood to the face;
  • Hair thinning;
  • Muscle pain.

You may rarely have severe side effects, such as:

  • Blurred vision or other eyesight changes;
  • Pain in the eyes;
  • Bruising or bleeding;
  • Nausea, vomiting, loss of appetite, yellow whites of the eyes;
  • Severe allergic reactions (difficulty breathing, rash, swelling).

If side effects increase or you experience severe side effects during treatment, see the doctor immediately.

Nolvadex: interaction with other drugs

Nolvadex may interact with other medications. So, before treatment, inform the doctor about all the medicines you take. Adverse effects are possible when combining it with these drugs:

  • Anticoagulants or blood thinners;
  • Estrogen-containing drugs;
  • Hormonal contraceptives;
  • SSRI antidepressants;
  • Anticonvulsants;
  • St. John's wort-based drugs.

It is not a complete list of drug interactions. For more information about possible interactions, check with a doctor or pharmacist and read the package insert for the drug.


Store Nolvadex at room temperature 20 - 25°С in a dark place out of the reach of children and animals. Don't use the drug if the expiration date has passed or the packaging is damaged.

The best offer for Nolvadex online on the market

We offer Nolvadex at an attractive price compared to other sellers. We guarantee the quality and safety of drugs at our online pharmacy. When ordering from us, you get these benefits:

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If you need help, you can contact our experts, who will answer all your questions.

How to buy Nolvadex online

You needn't go to the drugstore to buy Nolvadex. Buying Nolvadex online is possible in a few minutes at our pharmacy. To place an order, fill out an order form indicating the following information:

  • Drug name;
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  • Delivery address.

We will quickly complete your order and send it to the specified address. Our managers are in touch around the clock and will help you in case of any difficulties. Contact our support team now, and we will help you place your order.

Nolvadex Generic Testimonials

  • VE
    Vanessa Evans
    Verified review

    I always controlled my condition because my maternal relatives had breast cancer. I took the drug strictly on the recommendations of the doctor. Flushes, bone pain, and weight gain slightly spoiled my life. But that's nothing compared to not having cancer due to taking Nolvadex.

  • FP
    Forrest Perry
    Verified review

    I took steroids for a long time, which led to the risk of gynecomastia. My doctor prescribed me a small dose of Nolvadex (10 mg). So far, I have seen positive changes and hope I will get even better soon. The med distorted my test results on the thyroid function a little bit. It is a good thing I knew about this drug's features.

  • PR
    Piper Roberts
    Verified review

    The medication helps me feel better and continue to be active. But I had to give up my favorite tangerines. Turns out they're not compatible with the drug.

  • DS
    Dorothy Saunders
    Verified review

    So far, I have experienced only preventive benefits – more energy and overall well-being. The final results are very far… It's too early to tell cause I must take pills for a few years.

  • RL
    Rosie Long
    Verified review

    I was prescribed five years of pills after breast surgery. Now, I am 49, and I have taken the medication for the second year. I can share my life hacks to deal with side effects. If possible, be active because the drug promotes weight gain. But if you do exercise, it won't be a problem. No alcohol and greasy food, just a healthy diet. Also, I wear clothes made of natural fabrics, preferably cardigans with T-shirts to put off the top layer in case of hot flashes. I wish everyone a recovery. Stay strong.

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